Hugo Oliveira

Junior Researcher


Career

  • Since  2018: Junior Researcher, Universidade do Minho

Qualifications

  • 2014: PhD Program in Chemical and Biological Engineering, Universidade do Minho
  • Since 2018: Development of endolysins and depolymerases derived from bacteriophage for therapeutic purposes in combating gram-negative bacterial pathogens.
  • 2014 - 2018: Targeting A. baumannii infectious biofilms with a multivalent phage-based enzyme cocktail
  • 2010 - 2014: Molecular studies on bacteriophage endolysins and their potential to control Gram-negative bacteria

Projects

Past Students


Recent Publications

1
Predicting promoters in phage genomes using PhagePromoter
  • Bioinformatics, (In Press), 2019
2
Predicting promoters in phage genomes using machine learning models
  • Advances in Intelligent Systems and Computing, 1005 (PACBB 2019), 105-112, 2019
3
Staphylococci phages display vast genomic diversity and evolutionary relationships
  • BMC Genomics, 20(1), 357, 2019
4
Functional analysis and antivirulence properties of a new depolymerase from a myovirus that infects Acinetobacter baumannii capsule K45
  • Journal of Virology, 93(4), e01163-18, 2019
5
Efficacy and safety assessment of two enterococci phages in an in vitro biofilm wound model
  • Scientific Reports, 9(6643), 2019
6
Phage-derived peptidoglycan degrading enzymes: challenges and future prospects for in vivo therapy
  • Viruses, 10(6), 292, 2018
7
Ability of phages to infect Acinetobacter calcoaceticus-Acinetobacter baumannii complex species through acquisition of different pectate lyase depolymerase domains
  • Environmental Microbiology, 19(12), 5060-5077, 2017
8
A lytic Providencia rettgeri virus of potential therapeutic value is a deep-branching member of the T5virus genus
  • Applied and Environmental Microbiology, 83(23), e01567-17, 2017
9
  • Endersen, Lorraine; Buttimer, Colin; Nevin, Eoghan; Coffey, Aidan; Neve, Horst; Oliveira, Hugo; Lavigne, Rob; O'Mahony, Jim
Investigating the biocontrol and anti-biofilm potential of a three phage cocktail against Cronobacter sakazakii in different brands of infant formula
  • International Journal of Food Microbiology, 253, 1-11, 2017
10
Characterization and genomic analyses of two newly isolated Morganella phages define distant members among Tevenvirinae and Autographivirinae subfamilies
  • Scientific Reports, 7, 46157, 2017
11
  • Buttimer, Colin; Hendrix, Hanne; Oliveira, Hugo; Casey, Aidan; Neve, Horst; McAuliffe, Olivia; Ross, R. Paul; Hill, Colin; Noben, Jean-Paul; O'Mahony, Jim; Lavigne, Rob; Coffey, Aidan
Things Are Getting Hairy: Enterobacteria Bacteriophage vB_PcaM_CBB
  • Frontiers in Microbiology, 8(44), 2017
12
Characterization and genome sequencing of a Citrobacter freundii phage CfP1 harboring a lysin active against multidrug-resistant isolates
  • Applied Microbiology and Biotechnology, 100(24), 10543-10553, 2016
13
Bacteriophage-encoded depolymerases: their diversity and biotechnological applications
  • Applied Microbiology and Biotechnology, 100(5), 2141-2151, 2016
14
Structural and enzymatic characterization of ABgp46, a novel phage endolysin with broad anti-Gram-negative bacterial activity
  • Frontiers in Microbiology, 7(208), 1-9, 2016
15
Candida tropicalis biofilm and human epithelium invasion is highly influenced by environmental pH
  • Pathogens and Disease, 74(8), ftw101, 2016
16
Unexploited opportunities for phage therapy
  • Frontiers in Pharmacology, 6(180), 1-4, 2015
17
A thermostable salmonella phage endolysin, Lys68, with broad bactericidal properties against gram-negative pathogens in presence of weak acids
  • PLoS One, 9(10), e108376, 2014
18
  • Briers, Y.; Walmagh, M.; Van Puyenbroeck, V.; Cornelissen, A.; Cenens, W.; Aertsen, A.; Oliveira, H.; Azeredo, J.; Verween, G.; Pirnay, J.P.; Miller, S.; Volckaert, G.; Lavigne, R.
Engineered endolysin-based "artilysins" to combat multidrug-resistant gram-negative pathogens
  • mBio, 5(4), e01379-14, 2014
19
Molecular aspects and comparative genomics of bacteriophage endolysins
  • Journal of Virology, 87(8), 4558-4570, 2013
20
Bacteriophage endolysins as a response to emerging foodborne pathogens
  • Trends in Food Science & Technology, 28(2), 103-115, 2012
Full List