Ângela França

Post-Doc


Qualifications

  • 2013: PhD Program in Biomedical Engineering, Universidade do Minho

Laboratory Management


  • 2014 - 2021: Characterization of the molecular mechanisms behind S. epidermidis biofilm-released cells survival and evasion in human blood
  • 2009 - 2013: Characterization of the molecular interactions between Stapylococcus epideemidis biofilm infections and the host imune system

Research Students


Selected Publications

1
Assessment of Sep1virus interaction with stationary cultures by transcriptional and flow cytometry studies
  • FEMS Microbiology Ecology, 94(10), fiy143, 2018
2
Staphylococcus epidermidis wall teichoic acid confers tolerance to antibiotics and immune defense in human blood
  • ISSSI 2018 - International Symposium on Staphylococci and Staphylococcal Infections. No. P068, Copenhagen, Denmark, Aug 23-26, 166, 2018
3
Comparative analysis between biofilm formation and gene expression in Staphylococcus epidermidis isolates
  • Future Microbiology, 13(4), 415-427, 2018
4
Staphylococcus epidermidis is largely dependent on iron availability to form biofilms
  • International Journal of Medical Microbiology, 307(8), 552-563, 2017
5
Comparative transcriptomic analysis of Gardnerella vaginalis biofilms vs. planktonic cultures using RNA-seq
  • npj Biofilms and Microbiomes, 3(3), 1-7, 2017
6
Carvacrol is highly disruptive against coagulase-negative staphylococci in in vitro biofilms
  • Future Microbiology, 12(16), 1487-1496, 2017
7
Poly-N-acetylglucosamine production by Staphylococcus epidermidis cells increases their in vivo proinflammatory effect
  • Infection and Immunity, 84(10), 2933-2943, 2016
8
Staphylococcus epidermidis biofilm-released cells induce a prompt and more marked in vivo inflammatory-type response than planktonic or biofilm cells
  • Frontiers in Microbiology, 7(1530), 2016
9
Transcriptomic analysis of Staphylococcus epidermidis biofilm-released cells upon interaction with human blood circulating immune cells and soluble factors
  • Frontiers in Microbiology, 7(1143), 2016
10
Characterization of an in vitro fed-batch model to obtain cells released from S. epidermidis biofilms
  • AMB Express, 6(23), 2016
11
Plasma is the main regulator of Staphylococcus epidermidis biofilms virulence genes transcription in human blood
  • Pathogens and Disease, 74(2), ftv125, 2016
12
Using an in-vitro biofilm model to assess the virulence potential of Bacterial Vaginosis or non-Bacterial Vaginosis Gardnerella vaginalis isolates
  • Scientific Reports, 5(11640), 2015
13
Comparative proteomic and transcriptomic profile of Staphylococcus epidermidis biofilms grown in glucose-enriched medium
  • Talanta, 132, 705-712, 2015
14
Evidence for inter- and intra-species biofilm formation variability among a small group of coagulase-negative staphylococci
  • FEMS Microbiology Letters, 362(20), fnv175, 2015
15
Assessing and reducing sources of gene expression variability in Staphylococcus epidermidis biofilms
  • BioTechniques, 57(6), 295-301, 2014
16
Dormancy within Staphylococcus epidermidis biofilms: a transcriptomic analysis by RNA-seq
  • Applied Microbiology and Biotechnology, 98(6), 2585-2596, 2014
17
Dormant bacteria within Staphylococcus epidermidis biofilms have low inflammatory properties and maintain tolerance to vancomycin and penicillin after entering planktonic growth
  • Journal of Medical Microbiology, 63(Pt 10), 1274-1283, 2014
18
Alterations in the Staphylococcus epidermidis biofilm transcriptome following interaction with whole human blood
  • Pathogens and Disease, 70(3), 444-448, 2014
19
Farnesol induces cell detachment from established S. epidermidis biofilms
  • Journal of Antibiotics, 66, 255-258, 2013
20
Monoclonal antibody raised against PNAG has variable effects on static S. epidermidis biofilm accumulation in vitro
  • International Journal of Biological Sciences, 9(5), 518-520, 2013
21
Variability of RNA quality extracted from biofilms of foodborne pathogens using different kits impacts mRNA quantification by qPCR
  • Current Microbiology, 65(1), 54-59, 2012
22
Optimizing a qPCR gene expression quantification assay for S. epidermidis biofilms: a comparison between commercial kits and a customized protocol
  • PLoS One, 7(5), e37480, 2012
23
Comparison of RNA extraction methods from biofilm samples of Staphylococcus epidermidis
  • BMC Research Notes, 4, 572, 2011
24
Staphylococcus epidermidis biofilms with higher proportions of dormant bacteria induce a lower activation of murine macrophages
  • Journal of Medical Microbiology, 60(12), 1717-1724, 2011
25
Modulation of poly-N-acetylglucosamine accumulation within mature Staphylococcus epidermidis biofilms grown in excess glucose
  • Microbiology and Immunology, 10(55), 673-682, 2011
Full List