Lígia Rodrigues

Assistant Professor with Habilitation


  • Since  2017: Assistant Professor with Habilitation, Universidade do Minho
  • 2012 - 2017: Assistant Professor, Universidade do Minho
  • 2003 - 2012: Invited Assistant Professor, Universidade do Minho


  • 2005: PhD in Chemical and Biological Engineering, Universidade do Minho
  • 2001: Master Program on Biotechnology - Bioprocess Engineering, Universidade do Minho

Roles and Responsibilities

  • Since  2016: Vice-Head of Department, Department of Biological Engineering
  • Since  2011: Member of the Editorial Board of "Journal of Biotechnology & Biomaterials"

Laboratory Management

Teaching Interests


  • Innovation and Entrepreneurship in Biotechnology and Bioinformatics ( Master Program in Bioinformatics - Biological Sciences )
  • Food Science and Engineering ( Integrated Master in Biological Engineering )
  • Food Biotechnology ( Integrated Master in Biological Engineering )
  • Projet of Biological Engineering ( Integrated Master in Biological Engineering )
  • Introduction to Biomedical Engineering ( Integrated Master in Biomedical Engineering )

Research Interests

    Lígia R. Rodrigues is an Assistant Professor at University of Minho (UM, Portugal). She received her degree in Biological Engineering in 1997, her M.Sc. in Bioprocess Engineering in 2001 and her Ph.D. in Chemical and Biological Engineering in 2005 from the University of Minho. In 2006/2007 she was a post-doctoral research fellow at the three different universities (UM; IPATIMUP - University of Porto; University of Lund). Parts of her graduate, PhD and post-doctoral research were conducted in international labs and included the production and use of bioactive molecules for biomedical applications including anti-biofilm strategies, breast cancer diagnosis and prevention. In 2007, she joined the faculty of the Department of Biological Engineering (DEB) at UM as an invited assistant professor under the MIT-Portugal Program (until 2011). In 2008, she was a short-term visiting scholar at MIT, where she attended several Sloan-MIT MBA courses on Innovation, being also involved in the establishment of research collaborations between DEB and MIT research groups, and in the transference of good practices in Education and Innovation and Technology Licensing from MIT to Portuguese institutions. Since 2010, she integrated the Bioprocess Engineering and Computational Biosystems Group where she established her research group within the field of synthetic biology. Her current research interests are synthetic biology, cancer diagnosis and prevention, bioprocess development and functional food.

    Besides, Lígia has been involved in the launching of several spin-off companies in the Life Sciences field. She is one of the promoters and member of the administration of the spinoff company BIOTEMPO, Ltd., founded in 2002. BIOTEMPO is focused on the development and optimization of industrial biotech processes and the production of functional food ingredients. She was the CEO of BIOTEMPO from 2005 to 2007. As a representative of BIOTEMPO, Lígia was member of the executive board of PBIO – Portuguese Bioindustries Association. Moreover, she was a promoter and member of the administration of INCEPTION - Life Sciences Research and Development, Ltd., dedicated to the development of novel tools for cancer diagnosis (2013-2015).


Research Students

Recent Publications

In vitro digestibility and fermentability of fructo-oligosaccharides produced by Aspergillus ibericus
  • Journal of Functional Foods, 46, 278-287, 2018
Bioactivity of glycolipopeptide cell-bound biosurfactants against skin pathogens
  • International Journal of Biological Macromolecules, 109, 971-979, 2018
Improvement of biosurfactant production by Wickerhamomyces anomalus CCMA 0358 and its potential application in bioremediation
  • Journal of Hazardous Materials, 346, 152-158, 2018
Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
  • LWT - Food Science and Technology, 89, 58-64, 2018
Potential applications of the Escherichia coli heat shock response in synthetic biology
  • Trends in Biotechnology, 36(2), 186-198, 2018
New ß-galactosidase producers with potential for prebiotic synthesis
  • Bioresource Technology, 250, 131-139, 2018
Electrochemical aptasensor array for multiple detection of human osteopontin
  • Portugaliae Electrochimica Acta, 36(1), 1-9, 2018
Colorectal cancer cells increase the production of short chain fatty acids by Propionibacterium freudenreichii impacting on cancer cells survival
  • Frontiers in Nutrition, 5(44), 2018
Vineyard pruning waste as an alternative carbon source to produce novel biosurfactants by Lactobacillus paracasei
  • Journal of Industrial and Engineering Chemistry, 55, 40-49, 2017
The yeast-like fungus Aureobasidium thailandense LB01 produces a new biosurfactant using olive oil mill wastewater as an inducer
  • Microbiological Research, 204, 40-47, 2017
Physicochemical study of biomolecular interactions between lysosomotropic surfactants and bovine serum albumin
  • Colloids and Surfaces B: Biointerfaces, 159, 750-758, 2017
Sodium chloride effect on the aggregation behaviour of rhamnolipids and their antifungal activity
  • Scientific Reports, 7(12907), 2017
Electrochemical aptasensor for human osteopontin detection using a DNA aptamer selected by SELEX
  • Analytica Chimica Acta, 987, 25-37, 2017
β-galactosidase from Aspergillus lacticoffeatus: A promising biocatalyst for the synthesis of novel prebiotics
  • International Journal of Food Microbiology, 257, 67-74, 2017
Hydroxycinnamic acids and curcumin production in engineered Escherichia coli using heat shock promoters
  • Biochemical Engineering Journal, 125, 41-49, 2017
Novel cosmetic formulations containing a biosurfactant from Lactobacillus paracasei
  • Colloids and Surfaces B: Biointerfaces, 155, 522-529, 2017
New glycolipid biosurfactants produced by the yeast strain Wickerhamomyces anomalus CCMA 0358
  • Colloids and Surfaces B: Biointerfaces, 154, 373-382, 2017
Influence of nutritional and operational parameters on the production of butanol or 1,3-propanediol from glycerol by a mutant Clostridium pasteurianum
  • New Biotechnology, 34, 59-67, 2017
Optimization of fermentation conditions for the production of curcumin by engineered Escherichia coli
  • Journal of the Royal Society Interface, 14(133), 1-8, 2017
Biosurfactants in cosmetic formulations: trends and challenges
  • Critical Reviews in Biotechnology, 37(7), 911-923, 2017
Full List