Joana Castro

Junior Researcher


  • Since  2019: Junior Researcher, Universidade do Minho


  • 2018: Doutoramento Externo, Universidade do Minho
  • 2012: Integrated Master on Biomedical Engineering, Universidade do Minho
  • Since 2019: Targeting bacterial vaginosis multi-species biofilms through a Thymbra capitata based therapy
  • 2014 - 2018: Determining the pathogenic potential of commensal and clinical Gardnerella vaginalis isolates
  • 2011 - 2012: Adhesion of vaginal microorganisms to epithelial cells and its association with Bacterial Vaginosis


Research Students

Recent Publications

Innate immune components affect growth and virulence traits of bacterial-vaginosis-associated and non-bacterial-vaginosis-associated Gardnerella vaginalis strains similarly
  • Pathogens and Disease, 76(9), fty089, 2018
Lactobacillus crispatus represses vaginolysin expression by BV associated Gardnerella vaginalis and reduces cell cytotoxicity
  • Anaerobe, 50, 60-63, 2018
Unveiling the role of Gardnerella vaginalis in polymicrobial Bacterial Vaginosis (BV) biofilms: the impact of other vaginal pathogens living as neighbors
  • ISME Journal, 13, 1306-1317, 2018
Prevalence of bacterial vaginosis in Portuguese pregnant women and vaginal colonization by Gardnerella vaginalis
  • PeerJ, 5(e3750), 2017
Comparative transcriptomic analysis of Gardnerella vaginalis biofilms vs. planktonic cultures using RNA-seq
  • npj Biofilms and Microbiomes, 3(3), 1-7, 2017
Escherichia coli and Enterococcus faecalis are able to incorporate and enhance a pre-formed Gardnerella vaginalis biofilm
  • Pathogens and Disease, 74(3), ftw007, 2016
Bacterial vaginosis biofilms: challenges to current therapies and emerging solutions
  • Frontiers in Microbiology, 6(1528), 1-13, 2016
Using an in-vitro biofilm model to assess the virulence potential of Bacterial Vaginosis or non-Bacterial Vaginosis Gardnerella vaginalis isolates
  • Scientific Reports, 5(11640), 2015
Diagnosis of bacterial vaginosis by a new multiplex peptide nucleic acid fluorescence in situ hybridization method
  • PeerJ, 3(e780), 1-12, 2015
BV and non-BV associated Gardnerella vaginalis establish similar synergistic interactions with other BV-associated microorganisms in dual-species biofilms
  • Anaerobe, 36, 56-59, 2015
  • Ojala, Teija; Kankainen, Matti; Castro, Joana; Cerca, N.; Edelman, Sanna; Westerlund-Wikström, Benita; Paulin, Lars; Holm, Liisa; Auvinen, Petri
Comparative genomics of Lactobacillus crispatus suggests novel mechanisms for the competitive exclusion of Gardnerella vaginalis
  • BMC Genomics, 15(1070), 2014
Gardnerella vaginalis outcompetes 29 other bacterial species isolated from patients with bacterial vaginosis, using in an in vitro biofilm formation model
  • Journal of Infectious Diseases, 210(4), 593-596, 2014
Reciprocal interference between Lactobacillus spp. and Gardnerella vaginalis on initial adherence to epithelial cells
  • International Journal of Biomedical Science, 10(9), 1193-1198, 2013
Full List