Publications in International Journals / Series (Article (International))

Functionalized protein nanoemulsions by incorporation of chemically modified BSA

  • RSC Advances, 5(7), 4976-4983, 2015

Publisher: The Royal Society of Chemistry


The incorporation of bioactive compounds in stealth nanoparticles or nanoemulsions enhances their half-life in systemic circulation and can overcome the problems associated with the free drug. Bovine serum albumin (BSA)–drug conjugates were produced with either methotrexate (MTX), a potent anticancer agent, or vancomycin (VCM), a potent antibiotic. Those conjugates were used to produce functionalized BSA nanoemulsions in a formulation composed of an aqueous phase and an organic phase. BSA–folic acid (FA) conjugates were also produced allowing specific folate receptor (FR) mediated targeting of ...

CEB Authors



ISI Web of Science® Citations: 12


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