Publications in International Journals / Series (Article (International))

Orange IV stabilizes silk fibroin microemulsions

  • Engineering in Life Sciences, 15(4), 400-409, 2015

Publisher: Wiley-Blackwell

Abstract

Silk fibroin (SF) is a natural biopolymer that has been extensively studied in various applications due to its impressive mechanical properties and biocompatibility. Recently, SF-based particles have been proposed as controlled drug delivery systems. A new and efficient method to prepare SF microemulsions (SF-MEs) was developed by oil-in-water emulsions using high-pressure homogenization to promote emulsification. During SF-ME production, the secondary structure of SF changed to a more stable conformation (from random coil to β-sheets), thus allowing the formation of small and stable (140.7 ± ...

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