Publications in International Journals / Series (Article (International))

Effect of voriconazole on Candida tropicalis biofilms: Relation with ERG genes expression

  • MYCOPATHOLOGIA, 181(9), 643-651, 2016

Publisher: Springer Nature

Abstract

Candida tropicalis has emerged as the third most prevalent fungal pathogens and its ability to form biofilms has been considered one of the most important virulence factors, since biofilms represent high tolerance to antifungal agents. However, the mechanisms of C. tropicalis biofilm resistance to antifungals remain poorly understood. Thus, the main aim of this work was to infer about the effect of voriconazole on the formation and control of C. tropicalis biofilms and disclose its relationship with ERG genes' expression. Planktonic cells tolerance of several C. tropicalis clinical isolates to ...

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