Publications in Journals / Series (Article)

PEGylation greatly enhances laccase polymerase activity

  • ChemCatChem, (In Press), 2017

Publisher: Wiley-Blackwell

Abstract

Laccase catalyzes the oxidation and polymerization of phenolic compounds in the presence of oxygen. Herein, we report for the first time that a previous pegylation of laccase enhances the polymerase activity by 3-fold comparing with the native enzyme, as confirmed by UV-Vis spectroscopy. The polymerization of catechol increased only 1.5-fold when polyethyleneglycol (PEG) was added to the medium reaction. Molecular dynamic simulations suggest the formation of a miscible complex of polycatechol and PEG, which is responsible to push the reaction forward. In a negative control experiment set, all ...

CEB Authors

Groups

Links

Citations

ISI Web of Science® Citations: 0

0

Share Content