Publications in International Journals / Series (Article (International))

TiO2 nanotubes enriched with calcium, phosphorous and zinc: promising bio-selective functional surfaces for osseointegrated titanium implants

  • Alves, S.A.; Ribeiro, A.R.; Gemini-Piperni, S.; Silva, R.C.; Saraiva, A.M.; Leite, P.E.; Perez, G.; Oliveira, S.M.; Araujo, J.R.; Archanjo, B.S.; Rodrigues, M. Elisa; Henriques, Mariana; Celis, J.-P.; Shokuhfar, T.; Borojevic, R.; Granjeiro, J.M.; Rocha, L.A.
  • RSC Advances, 7(78), 49720-49738, 2017

Publisher: The Royal Society of Chemistry


The lack of osseointegration and implant-related infections are two major complications leading to failure of dental and orthopedic implants. Therefore, the development of effective titanium (Ti) implant surfaces able to display enhanced osteogenic activity and antimicrobial properties is required. In particular, titanium dioxide (TiO2) nanotubes (NTs) have demonstrated promising features to modulate biological responses, as they may be easily tailored to achieve multiple functions. This work aims to study the ability of bio-functionalized TiO2 NTs to induce osseointegration, and concomitantly ...

CEB Authors



ISI Web of Science® Citations: 3


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