Conference Proceedings (Abstracts in Conference Proceedings)

Bacteriophage encapsulated in nanohydroxyapatite-alginate hydrogel to prevent orthopedic devices-related infections

  • 28th European Conference on Biomaterials. Athens, Greece, Sep 4-8, 2017

Abstract

INTRODUCTION Device-associated infections represent one of the most serious and devastating complications in orthopaedic surgery and traumatology, with huge impact in morbidity, mortality, and medical costs underscoring the importance of prevention1. Given the variety of bacteria causing infections related to orthopaedic devices, emergence of bacteria resistant to antibiotics, virulence factors and cytotoxicity, new approaches for developing antimicrobial biomaterials are necessary2. Lytic bacteriophages have been proposed as alternative approach for treatment and prophylaxis of medical device ...

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