Publications in Journals / Series (Article)

Exploring anti-quorum sensing and anti-virulence based strategies to fight Candida albicans infections: an in silico approach

  • FEMS Yeast Research, (In Press), 2018

Publisher: Oxford University Press


The complex virulence attributes of Candida albicans are an attractive target to exploit in the development of new antifungals and anti-virulence strategies to combat C. albicans infections. Particularly, quorum-sensing (QS) has been reported as critical for virulence regulation in C. albicans. This work presents two knowledge networks with up-to-date information about QS regulation and experimentally tested anti-QS and anti-virulence agents for C. albicans. A semi-automatic bioinformatics workflow that combines literature mining and expert curation was used to retrieve otherwise scattered inf ...

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ISI Web of Science® Citations: 0


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