Conference Proceedings (Abstracts in Conference Proceedings)

Antisense oligomers based approaches for controlling Candida albicans filamentation

  • 14th ASM Conference on Candida and Candidiasis. No. 16A, Rhode Island, USA, April 15-19, 41, 2018

Abstract

Introduction: The increase of multidrug resistance of Candida pathogenic species to the traditional antifungal agents and the scarcity of new classes of antifungal drugs led to the increased of the number of infections caused by Candida albicans . One of the most relevant virulence factors attributed to C. albicans is their ability to switch from yeast to filamentous forms. These factors constitute a clinical problem, resulting in high morbidity and mortality, as well as, an economic burden associated with prolonged patients´ hospital stay. Thus, new strategies to manage Candida infections, wi ...

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