Publications in International Journals / Series (Article (International))

HABIT - a webserver for interactive T cell neoepitope discovery

  • bioRxiv, (In Press), 2019

Publisher: Cold Spring Harbor Laboratory

Abstract

Neoepitopes generated by amino acid variants specifically found in pathogens or cancer cells are gaining momentum in immunotherapy development. HABIT (HLA Binding InTelligence) is a web platform designed to generate and analyse machine learning-based T cell epitope predictions for improved neoepitope discovery. Availability and Implementation: HABIT is available at http://habit.evobiomed.com . Peptide-HLA binding predictions by NetMHCpan 4.0 and NetMHCIIpan 3.1 were implemented in a web application for interactive data exploration using shiny package powered by RStudio.

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