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Process development for the production of prebiotic fructo-oligosaccharides by Penicillium citreonigrum

  • Bioresource Technology, 282, 464-474, 2019

Publisher: Elsevier

Abstract

A new isolated P. citreonigrum URM 4459 was selected to produce fructooligosaccharides (FOS) in an efficient, economical and fast one-step fermentation. Optimal culture conditions were stablished by experimental design. Experiments run in bioreactor resulted in a high yield, content, productivity and purity of FOS (0.65 ± 0.06 gFOS.ginitial sucrose-1, 126.3 ± 0.1 g/L, 2.28 ± 0.08 g/L.h and 61 ± 0 %). The FOS mixture was purified up to 92 % (w/w) with an activated charcoal column. FOS produced were able to promote lactobacilli and bifidobacteria growth. Higher bacteria cell density was obtained ...

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