Publications in International Journals / Series (Article (International))

BSA-based sample clean-up columns for ochratoxin A determination in wine: method development and validation

  • Food Chemistry, 300(125204), 2019

Publisher: Elsevier


Analytical chromatographic techniques for mycotoxins control are well established, but they often depend on costly immunoaffinity sample clean-up. Serum albumins, particularly that from bovine origin (BSA), have stable binding affinity towards some mycotoxins, and can be cheaper alternative receptors for sample clean-up due to their wide availability. Thus, this work used BSA immobilized in agarose beads as a novel solid-phase extraction method for quantification of ochratoxin A (OTA) in wine. Constructed BSA-agarose columns could extract OTA efficiently from red wine after its dilution (4-fol ...

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