Bioprocess and Bionanotechnology

Leading Scientist


Main Topics of the Research Team

Asparaginase enzymes

Asparaginase enzymes

Development of formulations of asparaginases for leukaemia tailoring:

  • Low immune reactions.
  • Low ammonia production.
Elastase

Elastase

Development of detection methods for assessment in chronic wounds
Enzymatic transesterifications

Enzymatic transesterifications

Low water processes using soluble or immobilized esterase enzymes for production of:

  • Cellulose derivatives with fatty acids for textile applications.
  • Production of active components where a fatty acid is replaced by carboxylic drug in triacyl glycerol.
Enzyme polymerization of phenolics

Enzyme polymerization of phenolics

Laccase enzymes in nature have the function of breakdown lignin compounds into small aromatic compounds. The contact of these phenolic with laccase further oxidase them into a network of polyphenolic compounds.

Enzyme technology

Enzyme technology

Formulation of enzymes for industrial applications

Fibre bioprocesses

Fibre bioprocesses

Use of laccases/esterases/protease enzymes for modification of textiles. Work mainly done at College of Textiles, University Jiangnan, China.
Hair research

Hair research

Focus on development of peptides using microarray technology for controlling hair: shape, strength and humidity properties. The genetics basis of hair color and hair study is studied as well with collaboration with the department of biology.
Molecular Dynamics

Molecular Dynamics

Molecular dynamics Tools

For transdermal and hair delivery of active components.
For protein stability, interactions and docking and other tools.
Fine and coarse grain simulations are used depending on the complexity of the systems used.

Nano and micro-formulations

Nano and micro-formulations

Micro- and nano-scale systems have emerged as important tools for developing useful drug delivery systems. Biomacromolecules are exploited for this purpose such as proteins, polypeptides, nucleic acids, polysaccharides, co-polymers and phospholipids as potential building blocks for novel drug delivery systems. The research focus on the group it is mechanisms of formation of micro- and nano-scale capsules and shells, as well as on the functionalization of such structures for use in targeted delivery of bioactive materials. The focus of the group is the development of liposomal and emulsions vehicles for intravenous, intestinal and skin applications.