Centre of Biological Engineering / Centro de Engenharia Biológica

Carla Oliveira

Post-Doc

Research Line: Industrial Biotechnology and Bioengineering
Research Group: B.Factory
Lab.: Molecular Biotechnology Laboratory
253 601 973 (lab)
http://ceb.uminho.pt/People/Profile/carlaoliveira

Career

2018 - 2019: Junior Researcher, Universidade do Minho

Qualifications

2009: PhD Program in Chemical and Biological Engineering, Universidade do Minho
2005: Master Program on Biotechnology - Bioprocess Engineering, Universidade do Minho

2018 - 2019: Peptides for the determination of mycotoxins in food
2016 - 2019: Novel peptide-based technology for mycotoxins determination from food
2010 - 2016: Improving the properties of paper and textile fibers using recombinant glycosylated CBMs
2005 - 2009: Expression and production of recombinant frutalin in different expression systems and evaluation of its biomedical applications

Projects

Ongoing: BBRI - Biomass and Bioenergy Research Infrastructure (Team Member)

Research Students

Joana Maria Alves da Silva - Master Student
Marlene Isabel Cerqueira Baptista - Master Student

Recent Publications

1	Leal, Tânia; Abrunhosa, Luís; Domingues, Lucília; Venâncio, Armando; Oliveira, Carla BSA-based sample clean-up columns for ochratoxin A determination in wine: method development and validation Food Chemistry, 300(125204), 2019
2	Gomes, Sara; Bosco, Bartolomeo; Loureiro, Joana B.; Ramos, Helena; Raimundo, Liliana; Soares, Joana; Nazareth, Nair; Barcherini, Valentina; Domingues, Lucília; Oliveira, Carla; Bisio, Alessandra; Piazza, Silvano; Bauer, Matthias R.; Brás, João P.; Almeida, Maria Inês; Gomes, Célia; Reis, Flávio; Fersht, Alan R.; Inga, Alberto; Santos, Maria M. M.; Saraiva, Lucília SLMP53-2 restores wild-type-like function to mutant p53 through Hsp70: promising activity in hepatocellular carcinoma Cancers, 11(8), 1151, 2019
3	Silva, Rui; Aguiar, Tatiana Q.; Oliveira, Carla; Domingues, Lucília Physiological characterization of a pyrimidine auxotroph exposes link between uracil phosphoribosyltransferase regulation and riboflavin production in Ashbya gossypii New Biotechnology, 50, 1-8, 2019
4	Gomes, Ana Sara; Trovão, Filipa; Andrade Pinheiro, Benedita; Freire, Filipe; Gomes, Sara; Oliveira, Carla; Domingues, Lucília; Romão, Maria João; Saraiva, Lucília; Carvalho, Ana Luísa The crystal structure of the R280K mutant of human p53 explains the loss of DNA binding International Journal of Molecular Sciences, 19(4), 1184, 2018
5	Oliveira, Carla; Romaní, Aloia; Gomes, Daniel G.; Cunha, Joana T.; Gama, Miguel; Domingues, Lucília Recombinant family 3 carbohydrate-binding module as a new additive for enhanced enzymatic saccharification of whole slurry from autohydrolyzed eucalyptus globulus wood Cellulose, 25(4), 2505-2513, 2018
6	Oliveira, Carla; Domingues, Lucília Guidelines to reach high-quality purified recombinant proteins Applied Microbiology and Biotechnology, 102(1), 81-92, 2018
7	Oliveira, Hugo; Pinto, Graça; Oliveira, Ana; Oliveira, Carla; Faustino, Maria Alberta; Briers, Yves; Domingues, Lucília; Azeredo, Joana Characterization and genome sequencing of a Citrobacter freundii phage CfP1 harboring a lysin active against multidrug-resistant isolates Applied Microbiology and Biotechnology, 100(24), 10543-10553, 2016
8	Costa, V.L.D.; Costa, A.P.; Amaral, M.E.; Oliveira, Carla; Gama, F. Miguel; Dourado, Fernando; Simões, R.M. Effect of hot calendering on physical properties and water vapor transfer resistance of bacterial cellulose films Journal of Materials Science, 51(21), 9562-9572, 2016
9	Oliveira, Carla; Sepúlveda, Goreti; Aguiar, Tatiana Q.; Gama, F. Miguel; Domingues, L. Modification of paper properties using carbohydrate-binding module 3 from the Clostridium thermocellum CipA scaffolding protein produced in Pichia pastoris: elucidation of the glycosylation effect Cellulose, 22(4), 2755-2765, 2015
10	Oliveira, Carla; Carvalho, Vera; Domingues, L.; Gama, F.M. Recombinant CBM-fusion technology – applications overview Biotechnology Advances, 33(3-4), 358-369, 2015
11	Cunha, J.T.; Aguiar, Tatiana Q.; Romaní, A.; Oliveira, Carla; Domingues, L. Contribution of PRS3, RPB4 and ZWF1 to the resistance of industrial Saccharomyces cerevisiae CCUG53310 and PE-2 strains to lignocellulosic hydrolysate-derived inhibitors Bioresource Technology, 191, 7-16, 2015
12	Oliveira, C.M.; Teixeira, J.A.; Domingues, L. Recombinant production of plant lectins in microbial systems for biomedical application – the frutalin case study Frontiers in Plant Science, 5(390), 2014
13	Lopes, M.; Oliveira, C.M.; Domingues, L.; Mota, M.; Belo, I. Enhanced heterologous protein production in Pichia pastoris under increased air pressure Biotechnology Progress, 30(5), 1040-1047, 2014
14	Magalhães, F.; Aguiar, T.Q.; Oliveira, C.M.; Domingues, L. High-level expression of Aspergillus niger β-galactosidase in Ashbya gossypii Biotechnology Progress, 30(2), 261-268, 2014
15	Aguiar, T.Q.; Dinis, C.; Magalhães, F.; Oliveira, C.M.; Wiebe, M. G.; Penttilä, M.; Domingues, L. Molecular and functional characterization of an invertase secreted by Ashbya gossypii Molecular Biotechnology, 56(6), 524-534, 2014
16	Oliveira, Carla; Teixeira, J.A.; Domingues, L. Recombinant lectins: an array of tailor-made glycan-interaction biosynthetic tools Critical Reviews in Biotechnology, 33(1), 66-80, 2013
17	Wanderley, M.S.O.; Oliveira, C.M.; Bruneska, D.; Domingues, L.; Lima Filho, J.L.; Teixeira, J.A.; Mussatto, S.I. Influence of trace elements supplementation on the production of recombinant frutalin by Pichia pastoris KM71H in fed-batch process Chemical Papers, 67(7), 682-687, 2013
18	Castro, I.; Oliveira, C.; Domingues, L.; Teixeira, J.A.; Vicente, A.A. The effect of the electric field on lag phase, β-galactosidase production and plasmid stability of a recombinant Saccharomyces cerevisiae strain growing on lactose Food and Bioprocess Technology, 5(8), 3014-3020, 2012
19	Oliveira, Carla; Nicolau, Ana; Teixeira, José A.; Domingues, Lucília Cytotoxic effects of native and recombinant frutalin, a plant galactose-binding lectin, on HeLa cervical cancer cells Journal of Biomedicine and Biotechnology, 2011(ID 568932), 1-9, 2011
20	Oliveira, C.; Guimarães, P.M.R.; Domingues, L. Recombinant microbial systems for improved β-galactosidase production and biotechnological applications Biotechnology Advances, 29(6), 600-609, 2011

Full List

Carla Oliveira

Post-Doc

Career

Qualifications

Projects

Past Projects

Research Students

Past Students

Recent Publications

BSA-based sample clean-up columns for ochratoxin A determination in wine: method development and validation

SLMP53-2 restores wild-type-like function to mutant p53 through Hsp70: promising activity in hepatocellular carcinoma

Physiological characterization of a pyrimidine auxotroph exposes link between uracil phosphoribosyltransferase regulation and riboflavin production in Ashbya gossypii

The crystal structure of the R280K mutant of human p53 explains the loss of DNA binding

Recombinant family 3 carbohydrate-binding module as a new additive for enhanced enzymatic saccharification of whole slurry from autohydrolyzed eucalyptus globulus wood

Guidelines to reach high-quality purified recombinant proteins

Characterization and genome sequencing of a Citrobacter freundii phage CfP1 harboring a lysin active against multidrug-resistant isolates

Effect of hot calendering on physical properties and water vapor transfer resistance of bacterial cellulose films

Modification of paper properties using carbohydrate-binding module 3 from the Clostridium thermocellum CipA scaffolding protein produced in Pichia pastoris: elucidation of the glycosylation effect

Recombinant CBM-fusion technology – applications overview

Contribution of PRS3, RPB4 and ZWF1 to the resistance of industrial Saccharomyces cerevisiae CCUG53310 and PE-2 strains to lignocellulosic hydrolysate-derived inhibitors

Recombinant production of plant lectins in microbial systems for biomedical application – the frutalin case study

Enhanced heterologous protein production in Pichia pastoris under increased air pressure

High-level expression of Aspergillus niger β-galactosidase in Ashbya gossypii

Molecular and functional characterization of an invertase secreted by Ashbya gossypii

Recombinant lectins: an array of tailor-made glycan-interaction biosynthetic tools

Influence of trace elements supplementation on the production of recombinant frutalin by Pichia pastoris KM71H in fed-batch process

The effect of the electric field on lag phase, β-galactosidase production and plasmid stability of a recombinant Saccharomyces cerevisiae strain growing on lactose

Cytotoxic effects of native and recombinant frutalin, a plant galactose-binding lectin, on HeLa cervical cancer cells

Recombinant microbial systems for improved β-galactosidase production and biotechnological applications

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Carla Oliveira

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