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Decalactone production by Yarrowia lipolytica under increased O2 transfer rates
- Águedo, M.; Gomes, N.; Escamilla Garcia, E.; Waché, Y.; Mota, M.; Teixeira, J.A.; Belo, I.
- Biotechnology Letters, 27(20), 1617-1621, 2005
Publisher: Springer Nature
Abstract
Yarrowia lipolytica converts methyl ricinoleate to γ-decalactone, a high-value fruity aroma compound. The highest amount of 3-hydroxy-γ-decalactone produced by the yeast (263 mg lˉ¹) occurred by increasing the kLa up to 120 hˉ¹ at atmospheric pressure; above it, its concentration decreased, suggesting a predominance of the activity of 3- ydroxyacyl-CoA dehydrogenase. Cultures were grown under high-pressure, i.e., under increased O2 solubility, but, although growth was accelerated, γ-decalactone production decreased. However, by applying 0.5 MPa during growth and biotransformation gave increas ...
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