Functionality, bioavailability and toxicity of food systems

Digestion, delivery, functionality and safety of novel food systems need a comprehensive and integrative assessment. The relationship between food structure design and bioavailability of its main macronutrients has been established by our research team.


Main Topics of the Research Team

Evaluation of cytotoxicity/cytocompatibility

Evaluation of cytotoxicity/cytocompatibility

of the produced micro and nano scale structures from food-grade materials using in vitro cell line models (such as, Caco-2)

that mimics the human intestinal epithelium monolayer. Also, bioactive compounds’ and micro and nano scale structures’ permeability through intestinal epithelial cell culture in vitro models has been assessed.

In vitro gastrointestinal digestion using both static and dynamic models

In vitro gastrointestinal digestion using both static and dynamic models

that reproduce the compartments of the human stomach and small intestine

in the case of the dynamic model, also, the sequential secretions’ addition and passive absorption of small molecules/water through a hollow fibre system.