Publications in International Journals / Series (Article (International))
Biomimetic aqueous-core lipid nanoballoons integrating a multiple emulsion formulation: A suitable housing system for viable lytic bacteriophages
- Balcão, Victor M.; Glasser, Cássia A.; Chaud, Marco V.; del Fiol, F.S.; Tubino, Matthieu; Vila, Marta M.D.C.
- Colloids and Surfaces B-Biointerfaces, 123, 478-485, 2014
Publisher: Elsevier
Abstract
The emergence of antibiotic-resistant bacterial strains and the weak penetration of antibiotics into bacterial biofilms put an emphasis in the need for safe and effective alternatives for antimicrobial treatments. The application of strictly lytic bacteriophages (or phages) has been proposed as an alternative (or complement) to conventional antibiotics, allowing release of the natural predators of bacteria directly to the site of infection. In the present research effort, production of bacteriophage derivatives (starting from lytic phage particle isolates), encompassing full stabilization of t ...
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