Book Part (Book Chapter)
Chapter 30 - Natural biopolymer scaffolds for bacteriophage delivery in the medical field
- Pinto, Ana Mafalda; Dias, Marisol; Pastrana, Lorenzo M.; Miguel A. Cerqueira; Sanna Sillankorva
- In K. Pal, S. Verma, P. Datta, A. Barui, S.A.R. Hashmi, A.K. Srivastava. Advances in Biomedical Polymers and Composites, Elsevier, 2023. ISBN: 978-0-323-88524-9, 769-793
Publisher: Elsevier
Abstract
Phages have sparked attention as an appealing way to eradicate bacteria serving as a possible treatment option for diseases caused by antibiotic- and multidrug-resistant pathogens. However, the susceptibility of phages to acidic pH, enzymatic activity, and short in vivo half-life largely restricts their use. Phages loaded into biomaterials will be protected from harmful environmental elements while being released for therapeutic action. Furthermore, biomaterials can react to an emerging infection before clinical symptoms appear, substantially improving the patient’s prognosis. Thus phage-impre ...
CEB Authors
Groups
CEB is supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding UIDB/04469/2020.
2025 © CEB - Centre of Biological Engineering. All Rights Reserved.
