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Construction of a biocompatible and antioxidant multilayer coating by layer-by-layer assembly of κ-carrageenan and quercetin nanoparticles

  • Souza, Marthyna P.; Vaz, Antônio F. M.; Costa, Thacianna B.; Cerqueira, Miguel A.; De Castro, Célia M. M. B.; Vicente, António A.; Carneiro-da-Cunha, Maria G.

Publisher: Springer Nature

Abstract

The present work aimed at the construction and characterization of a multilayer coating based on κ-carrageenan and quercetin-loaded lecithin/chitosan nanoparticles (Np) by the layer-by-layer technique and the evaluation of its antioxidant capacity and potential cytotoxicity in vitro. The multilayered coating was successfully self-assembled, as confirmed by UV-Vis spectroscopy, contact angle, atomic force microscopy (AFM), and scanning electron microscopy (SEM). Multilayered coatings showed to have antioxidant capacity, with a DPPH• radical scavenging activity of 31.32 ± 3.13% and a result of t ...

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