Isabel Rocha

Assistant Professor


  • Since  2011: Assistant Professor, Universidade do Minho
  • 2006 - 2011: Invited Assistant Professor, Universidade do Minho
  • 2004 - 2006: Invited Lecturer, Universidade do Minho


  • 2003: PhD in Chemical and Biological Engineering, Universidade do Minho

Roles and Responsibilities

  • Since  2011: Member of the Scientific Steering Committee of Department, Department of Biological Engineering
  • 2010 - 2013: Program Director, Master Program in Bioinformatics - Biological Sciences
  • Since  2007: Member of Program Studies Steering Committee, PhD Program in Bioengineering
  • 2008 - 2008: APBio
  • Since  2013: Member of the Editorial Board of "Frontiers in Bioengineering and Biotechnology - Synthetic Biology"

Laboratory Management

Honors and Awards

  • 2011: Best Poster Award at 5th Annual Workshop on the Business-Government Interface: Systems and Synthetic Biology, Universidade do Minho, Braga. Title: Exploring the gap between dynamic and constraint-based models of metabolism.


Research Students

Recent Publications

Quantitative physiology and elemental composition of Kluyveromyces lactis CBS 2359 during growth on glucose at different specific growth rates
  • Antonie van Leeuwenhoek - Journal of Microbiology, 111(2), 183-195, 2018
Impact of the cultivation strategy on resveratrol production from glucose in engineered Corynebacterium glutamicum
  • Journal of Biotechnology, 265, 70-75, 2018
An adsorptive bioprocess for production and recovery of resveratrol with Corynebacterium glutamicum
  • Journal of Chemical Technology and Biotechnology, (In Press), 2018
  • Dudnik, Alexey; Almeida, A. Filipa; Andrade, Ricardo; Avila, Barbara; Bañados, Pilar; Barbay, Diane; Bassard, Jean-Etienne; Benkoulouche, Mounir; Bott, Michael; Braga, Adelaide; Breitel, Dario; Brennan, Rex; Bulteau, Laurent; Chanforan, Celine; Costa, Inês; Costa, Rafael S.; Doostmohammadi, Mahdi; Faria, Nuno; Feng, Chengyong; Fernandes, Armando; Ferreira, Patricia; Ferro, Roberto; Foito, Alexandre; Freitag, Sabine; Garcia, Gonçalo; Gaspar, Paula; Godinho-Pereira, Joana; Hamberger, Björn; Hartmann, András; Heider, Harald; Jardim, Carolina; Julien-Laferriere, Alice; Kallscheuer, Nicolai; Kerbe, Wolfgang; Kuipers, Oscar P.; Li, Shanshan; Love, Nicola; Marchetti-Spaccamela, Alberto; Marienhagen, Jan; Martin, Cathie; Mary, Arnaud; Mazurek, Vincent; Meinhart, Camillo; Sevillano, David Méndez; Menezes, Regina; Naesby, Michael; Nørholm, Morten H. H.; Okkels, Finn T.; Oliveira, Joana; Ottens, Marcel; Parrot, Delphine; Pei, Lei; Rocha, Isabel; Rosado-Ramos, Rita; Rousseau, Caroline; Sagot, Marie-France; dos Santos, Claudia Nunes; Schmidt, Markus; Shelenga, Tatiana; Shepherd, Louise; Silva, Rita M.; da Silva, Marcelo Henriques; Stahlhut, Steen Gustav; Simon, Olivier; Solopova, Ana; Sorokin, Artem; Stewart, Derek; Stougie, Leen; Su, Shang; Thole, Vera; Tikhonova, Olga; Trick, Martin; Vain, Philippe; Veríssimo, André; Vila-Santa, Ana; Vinga, Susana; Vogt, Michael; Wang, Liangsheng; Wang, Lijin; Wei, Wei; Youssef, Sandra; Neves, Ana Rute; Forster, Jochen
BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
  • Phytochemistry Reviews, (In Press), 2018
Genome-scale modeling of yeast: chronology, applications and critical perspectives
  • FEMS Yeast Research, 17(5), fox050, 2017
Development of a framework for metabolic pathway analysis-driven strain optimization methods
  • Interdisciplinary Sciences-Computational Life Sciences, 9(1), 46-55, 2017
Integration of biomass formulations of genome-scale metabolic models with experimental data reveals universally essential cofactors in prokaryotes
  • Metabolic Engineering, 39, 200-208, 2017
Genome-wide semi-automated annotation of transporter systems
  • IEEE-ACM Transactions on Computational Biology and Bioinformatics, 14(2), 443-456, 2017
Rhodococcus opacus B4: a promising bacterium for production of biofuels and biobased chemicals
  • AMB Express, 6(35), 1-11, 2016
Improving the flux distributions simulated with genome-scale metabolic models of Saccharomyces cerevisiae
  • Metabolic Engineering Communications, 3, 153-163, 2016
Estimation of biomass composition from genomic and transcriptomic information
  • Journal of Integrative Bioinformatics, 13(2), 285, 2016
  • Faria, José Pedro; Davis, James J.; Edirisinghe, Janaka N.; Taylor, Ronald C.; Weisenhorn, Pamela; Olson, Robert D.; Stevens, Rick L.; Rocha, Miguel; Rocha, Isabel; Best, Aaron A.; DeJongh, Matthew; Tintle, Nathan L.; Parrello, Bruce; Overbeek, Ross; Henry, Christopher S.
Computing and applying atomic regulons to understand gene expression and regulation
  • Frontiers in Microbiology, 7(1819), 1-14, 2016
Stoichiometric representation of gene–protein–reaction associations leverages constraint-based analysis from reaction to gene-level phenotype prediction
  • PLoS Computational Biology, 12(10:e1005140), 1-24, 2016
Current state and challenges for dynamic metabolic modeling
  • Current Opinion in Microbiology, 33, 97-104, 2016
  • Jouhten, Paula; Boruta, T.; Andrejev, S.; Pereira, Filipa; Rocha, Isabel; Patil, K.R.
Yeast metabolic chassis designs for diverse biotechnological products
  • Scientific Reports, 6(29694), 1-9, 2016
In silico constraint-based strain optimization methods: the quest for optimal cell factories
  • Microbiology and Molecular Biology Reviews, 80(1), 45-67, 2016
A comparative analysis of dynamic models of the central carbon metabolism of Escherichia coli
  • IFAC-PapersOnLine, 49(26), 270-276, 2016
A comparative proteome analysis of Escherichia coli ΔrelA mutant cells
  • Frontiers in Bioengineering and Biotechnology, 4(78), 1-12, 2016
Reconstruction of the regulatory network for Bacillus subtilis and reconciliation with gene expression data
  • Frontiers in Microbiology, 7(275), 1-11, 2016
Extracting kinetic information from literature with KineticRE
  • Journal of Integrative Bioinformatics, 12(4), 282, 2015
Full List